Biomarkers for Hemorrhages Associated with Slipped Discs in French Bulldogs
OpenStudy Goals
Ethos Discovery seeks to investigate biomarkers associated with hemorrhages (bleeding) in French Bulldogs following slipped discs in their back. We would like to collect blood samples from each of the two identified eligible groups (see below) to perform genetic testing that will give us insight and help improve outcomes for future patients of all breeds.
CONDITION OVERVIEW
Recent research published by Wheat Ridge Animal Hospital shows that:
- Two out of three French Bulldogs have bleeding with slipped discs in their back.
- Dogs with bleeding usually progress rapidly (typically unable to walk within 24-48 hours).
- Dogs with bleeding are more likely to be paralyzed and lose feeling in their toes.
- Long-term outcomes are worse in dogs with bleeding.
These points, as well as an increase in breed popularity, has resulted in a large number of recent cases in French Bulldogs, creating a growing amount of attention and concern from veterinarians. It is known that slipped disc-related hemorrhages may contribute to neurologic deterioration. The toxic effects of the hemorrhage and blood breakdown on the brain and spinal cord are suspected to contribute to the progression and severity of the neurological effects, such as lack of mobility/paralysis and loss of feeling in extremities.
WHAT TO EXPECT
You would be expected to bring your French Bulldog into Wheat Ridge Animal Hospital for a small amount of blood to be collected for genetic analysis.
ELIGIBILITY CRITERIA
- French Bulldogs that are 6+ years old that have never had a disc herniation.
OR
- French Bulldogs of ANY AGE that have had a previous disc herniation confirmed by MRI or surgery.
Interested?
Enroll or request more information below